Type 2 diabetes as an inflammatory disease

[Jhanananda]

With me adding Anthocyanin to my diet about 9 months ago, might partially explain why my type 2 diabetes seems to have gone into remission.
Type 2 diabetes as an inflammatory disease

Abstract

Components of the immune system are altered in obesity and type 2 diabetes (T2D), with the most apparent changes occurring in adipose tissue, the liver, pancreatic islets, the vasculature and circulating leukocytes. These immunological changes include altered levels of specific cytokines and chemokines, changes in the number and activation state of various leukocyte populations and increased apoptosis and tissue fibrosis. Together, these changes suggest that inflammation participates in the pathogenesis of T2D. Preliminary results from clinical trials with salicylates and interleukin-1 antagonists support this notion and have opened the door for immunomodulatory strategies for the treatment of T2D that simultaneously lower blood glucose levels and potentially reduce the severity and prevalence of the associated complications of this disease.

Type 2 diabetes is an inflammatory disease, say researchers

New research from Denmark adds further weight to the idea that type 2 diabetes is an inflammatory disease.

The recently published study describes how in mice, during the very early stages of type 2 diabetes, immune cells called macrophages invade pancreatic tissue, releasing large quantities of cytokines - pro-inflammatory proteins - that help destroy insulin-producing beta cells.

More than 360 million people around the world have type 2 diabetes, including around 8% of Americans. The disease can lead to more serious conditions like cardiovascular disease, blindness, loss of limbs, and kidney failure.

In people who are healthy and do not have diabetes, the beta cells of the pancreas secrete insulin into the bloodstream - this helps to regulate blood sugar levels which rise after eating.

One of the researchers, Dr. Alexander Rosendahl, from the Department of Diabetes Complication Biology at Novo Nordisk A/S, in Malov, says:

    "The study may provide novel insights allowing development of tailor-made anti-inflammatory based therapies reducing the burden of type 2 patients."

[bodhimind]

Very interesting. My father suffers from type II diabetes so I've been trying to help him with it. Thanks for the information.

[Jhanananda]

You are welcome bodhimind.  My conclusions regarding my own success with normalizing my blood sugar are:
1] There is a lifestyle and diet that leads to Type 2 diabetes, which means there is a lifestyle and diet that leads away from Type 2 diabetes.
2] The lifestyle and diet that leads to Type 2 diabetes has certain characteristics: They are: high carb, low chromium intake, and a background of inflammation.
3] The lifestyle and diet that leads away from Type 2 diabetes has certain characteristics:  It is: low carb diet, high chromium intake, and a reduction of inflammation.
4]  The low carb diet is well describe in the literature.  It just takes discipline and willingness to take one's morning blood sugar reading before eating, and logging it; however I found it incomplete for my recovery from Type 2 diabetes.
5] Chromium supplementation is also needed.  Eggs in the diet every day are very possibly all that is needed; however, nutritional yeast seems to have helped me.
6] There is research that supports 2 seasoning reduce blood sugar.  They are: cinnamon and ginger.  I recently added cinnamon to my diet, and my blood sugar has been lowered, so it might be part of my recovery.  I plan to add ginger to my daily diet in about a week after I have developed a new blood sugar baseline.